North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations Part II: Topical, intralesional, and systemic medical management

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

卷:81

Article

Alikhan, Ali¹  Sayed, Christopher²  Alavi, Afsaneh³  Alhusayen, Raed³  Brassard, Alain⁴  Burkhart, Craig²  Crowell, Karen⁵  Eisen, Daniel B.⁴  Gottlieb, Alice B.⁶  Hamzavi, Iltefat⁷  Hazen, Paul G.⁸  Jaleel, Tara⁹  Kimball, Alexa B.¹⁰  Kirby, Joslyn¹¹  Lowes, Michelle A.¹²  Micheletti, Robert^13,14  Miller, Angela⁷  Naik, Haley B.¹⁵  Orgill, Dennis¹⁶  Poulin, Yves¹⁷ 

[1] Sutter Hlth, Sacramento, CA USA

[2] Univ N Carolina, Dept Dermatol, Chapel Hill, NC 27515 USA

[3] Univ Toronto, Div Dermatol, Dept Med, Toronto, ON, Canada

[4] Univ Calif Davis, Dept Dermatol, Sacramento, CA 95817 USA

[5] Univ N Carolina, Sch Med, Hlth Sci Lib, Chapel Hill, NC 27515 USA

[6] Mt Sinai Hosp, Icahn Sch Med, Dept Dermatol, New York, NY 10029 USA

[7] Henry Ford Hosp, Dept Dermatol, Detroit, MI 48202 USA

[8] Associates Dermatol, Westlake, OH USA

[9] Duke Univ, Sch Med, Dept Dermatol, Durham, NC USA

[10] Harvard Med Sch, Dept Dermatol, Boston, MA 02115 USA

[11] Penn State Hershey Med Ctr, Dept Dermatol, Hershey, PA USA

[12] Lab Invest Dermatol, New York, NY USA

[13] Univ Penn, Perelman Sch Med, Dept Dermatol, Philadelphia, PA 19104 USA

[14] Univ Penn, Perelman Sch Med, Dept Med, Philadelphia, PA 19104 USA

[15] Univ Calif San Francisco, Dept Dermatol, San Francisco, CA 94143 USA

[16] Brigham & Womens Hosp, Div Plast Surg, 75 Francis St, Boston, MA 02115 USA

[17] Ctr Rech Dermatol Quebec Metropolitain, Quebec City, PQ, Canada

关键词: acne inversa;    adalimumab;    biomarkers;    carbon dioxide laser;    clindamycin;    comorbidities;    ertapenem;    finasteride;    guidelines;    hidradenitis suppurativa;    infliximab;    laser;    lifestyle modification;    microbiome;    Nd:YAG;    oral contraceptive pills;    rifampin;    spironolactone;   

DOI  :  10.1016/j.jaad.2019.02.068

来源: Elsevier

【 摘 要 】

Hidradenitis suppurativa is a severe and debilitating dermatologic disease. Clinical management is challenging and consists of both medical and surgical approaches, which must often be combined for best outcomes. Therapeutic approaches have evolved rapidly in the last decade and include the use of topical therapies, systemic antibiotics, hormonal therapies, and a wide range of immunomodulating medications. An evidence-based guideline is presented to support health care practitioners as they select optimal medical management strategies and is reviewed in this second part of the management guidelines. A therapeutic algorithm informed by the evidence available at the time of the review is provided.

【 授权许可】

Free