Soapstone reinforced hydroxyapatite coatings for biomedical applications

SURFACE & COATINGS TECHNOLOGY

卷:397

Article

Mota, Laureana Moreira¹  Nunes Nicomedes, Daniel Nilson¹  Moreira Barboza, Ana Paula¹  Lima de Moraes Ramos, Sergio Luis²  Vasconcellos, Rebecca³  Medrado, Nathanael Vieira³  de Alvarenga, Erika Costa^3,4  Machado, Giovanna⁵  Juste, Karyne R. C.⁶  de Vasconcelos, Claudia Karina^7,10  Righi, Ariete⁸  Manhabosco, Sara Matte⁹  Resende, Rodrigo Ribeiro³  Campos Batista, Ronaldo Junio¹  Soares, Jaqueline dos Santos¹  Manhabosco, Taise Matte¹ 

[1] Univ Fed Ouro Preto, Dept Fis, Campus Univ Morro do Cruzeiro ICEB DEFIS, BR-35400000 Ouro Preto, MG, Brazil

[2] Univ Fed Minas Gerais, Ctr Tecnol Nanomat & Grafeno CTNano, BR-31270901 Belo Horizonte, MG, Brazil

[3] Univ Fed Minas Gerais, Inst Ciencia Biol, Dept Bioquim & Imunol, Lab Sinalizacao Celular & Nanobiotecnol, Av Antonio Carlos 6627, BR-31270901 Belo Horizonte, MG, Brazil

[4] Univ Fed Sao Joao Del Rei, Dept Ciencias Nat, Preca Dom Helvecio 74, BR-36301160 Sao Joao Del Rei, MG, Brazil

[5] Ctr Tecnol Estrateg Nordeste CETENE, Av Prof Luis Freire 01, BR-50740540 Recife, PE, Brazil

[6] Inst SENAI Inovacao Engn Superficies, Rua Sete 2000, BR-31035536 Belo Horizonte, MG, Brazil

[7] Pontificia Univ Catolica Minas Gerais, Dept Fis & Quim, Av Dom Jose Gaspar 500, BR-30535901 Belo Horizonte, MG, Brazil

[8] Univ Fed Minas Gerais, Dept Fis, BR-31270901 Belo Horizonte, MG, Brazil

[9] Univ Fed Rio Grande, Lab Metrol, Campus Carreiros,Av Italia,Km 8, BR-96203900 Rio Grande, RS, Brazil

[10] Pontificia Univ Catolica Minas Gerais, Dept Engn Quim, Av Dom Jose Gaspar 500, BR-30535901 Belo Horizonte, MG, Brazil

关键词: Soapstone talc;    Pulsed electrodeposition;    Hydroxyapatite;    Biocompatibility;   

DOI  :  10.1016/j.surfcoat.2020.126005

来源: Elsevier

【 摘 要 】

Mechanical resistant bioactive materials are of high interest for biomedical applications. In this work, we address the improvement in mechanical properties of HA coatings by the addition of a cheap and widely available secondary phase material, the talc from soapstone. The composites hydroxyapatite/talc (HA/talc) were successfully obtained by pulsed electrodeposition and characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, Raman spectroscopy, corrosion and wear resistance and biocompatibility tests. We found that the addition of talc greatly improves the mechanical properties of coatings (i. e., wear track and friction coefficient in wear tests were significantly diminished) without diminishing corrosion resistance and biocompatibility. Alamar Blue (R) tests, alkaline phosphatase activity, and collagen production indicate that the biocomposites are biocompatible and talc itself induce bone maturation.

【 授权许可】

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