期刊论文详细信息
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 卷:77
Semilunar Valve Interventions for Congenital Heart Disease
Review
Morray, Brian H.1  McElhinney, Doff B.2,3 
[1] Seattle Childrens Hosp, Div Pediat Cardiol, Seattle, WA USA
[2] Lucile Packard Childrens Hosp Stanford, Dept Cardiothorac Surg, Palo Alto, CA USA
[3] Lucile Packard Childrens Hosp Stanford, Dept Pediat Cardiol, Palo Alto, CA USA
关键词: aortic valve;    pulmonary valve;    tetralogy of Fallot;    transcatheter valve replacement;    valvuloplasty;   
DOI  :  10.1016/j.jacc.2020.10.052
来源: Elsevier
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【 摘 要 】

Transcatheter balloon valvuloplasty for the treatment of aortic and pulmonary valve stenosis was first described nearly 40 years ago. Since that time, the technique has been refined in an effort to optimize acute outcomes while reducing the longterm need for reintervention and valve replacement. Balloon pulmonary valvuloplasty is considered first-line therapy for pulmonary valve stenosis and generally results in successful relief of valvar obstruction. Larger balloon to annulus (BAR) diameter ratios can increase the risk for significant valvar regurgitation. However, the development of regurgitation resulting in right ventricular dilation and dysfunction necessitating pulmonary valve replacement is uncommon in long-term follow-up. Balloon aortic valvuloplasty has generally been the first-line therapy for aortic valve stenosis, although some contemporary studies have documented improved outcomes following surgical valvuloplasty in a subset of patients who achieve tri-leaflet valve morphology following surgical repair. Over time, progressive aortic regurgitation is common and frequently results in the need for aortic valve replacement. Neonates with critical aortic valve stenosis remain a particularly high-risk group. More contemporary data suggest that acutely achieving an aortic valve gradient <35 mm Hg with mild aortic regurgitation may improve long-term valve performance and reduce the need for valve replacement. Continued study will help to further improve outcomes and reduce the need for future reinterventions. (C) 2021 by the American College of Cardiology Foundation.

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