Management of Acute and Recurrent Pericarditis JACC State-of-the-Art Review

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

卷:75

Review

Chiabrando, Juan Guido^1,2  Bonaventura, Aldo^1,3  Vecchie, Alessandra^1,3  Wohlford, George F.⁴  Mauro, Adolfo G.¹  Jordan, Jennifer H.^1,5  Grizzard, John D.⁶  Montecucco, Fabrizio^3,7  Berrocal, Daniel Horacio²  Brucato, Antonio⁸  Imazio, Massimo⁹  Abbate, Antonio¹ 

[1] Virginia Commonwealth Univ, VCU Pauley Heart Ctr, Richmond, VA USA

[2] Hosp Italiano Buenos Aires, Dept Cardiol, Buenos Aires, DF, Argentina

[3] Univ Genoa, Dept Internal Med, Clin Internal Med 1, Genoa, Italy

[4] Virginia Commonwealth Univ, VCU Sch Pharm, Richmond, VA USA

[5] Virginia Commonwealth Univ, Dept Biomed Engn, Richmond, VA USA

[6] Virginia Commonwealth Univ, Dept Radiol, Richmond, VA USA

[7] IIRCCS Osped Policlin San Martino, Genova Italian Cardiovasc Network, Genoa, Italy

[8] Univ Milan, Osped Fatebenefratelli, Dept Biomed & Clin Sci Sacco, Milan, Italy

[9] Univ Cardiol, AOU Citta Salute & Sci Torino, Turin, Italy

关键词: acute pericarditis;    cardiac tamponade;    constrictive pericarditis;    recurrent pericarditis;    treatment;   

DOI  :  10.1016/j.jacc.2019.11.021

来源: Elsevier

【 摘 要 】

Pericarditis refers to the inflammation of the pericardial layers, resulting from a variety of stimuli triggering a stereotyped immune response, and characterized by chest pain associated often with peculiar electrocardiographic changes and, at times, accompanied by pericardial effusion. Acute pericarditis is generally self-limited and not life-threatening; yet, it may cause significant short-term disability, be complicated by either a large pericardial effusion or tamponade, and carry a significant risk of recurrence. The mainstay of treatment of pericarditis is represented by anti-inflammatory drugs. Anti-inflammatory treatments vary, however, in both effectiveness and side-effect profile. The objective of this review is to summarize the up-to-date management of acute and recurrent pericarditis. (C) 2020 by the American College of Cardiology Foundation.

【 授权许可】

Free