Prevalence and Causes of Fatal Outcome in Catheter Ablation of Atrial Fibrillation

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

卷:53

Article

Cappato, Riccardo¹  Calkins, Hugh²  Chen, Shih-Ann³  Davies, Wyn⁴  Iesaka, Yoshito⁵  Kalman, Jonathan⁶  Kim, You-Ho⁷  Klein, George⁸  Natale, Andrea⁹  Packer, Douglas¹⁰  Skanes, Allan⁸ 

[1] IRCCS Policlin San Donato, Arrhythmias & Electrophysiol Ctr, Milan, Italy

[2] Johns Hopkins Univ, Sch Med, Baltimore, MD USA

[3] Vet Gen Hosp, Taipei, Taiwan

[4] St Marys Hosp, London, England

[5] Tsuchiura Kyodo Gen Hosp, Ctr Cardiovasc, Tsuchiura, Ibaraki, Japan

[6] Royal Melbourne Hosp, Parkville, Vic 3050, Australia

[7] Asan Med Ctr, Dept Cardiol, Seoul, South Korea

[8] Univ Western Ontario, Univ Hosp, Dept Cardiol, London, ON N6A 5A5, Canada

[9] St Davids Med Ctr, Texas Arrhythmia Inst, Austin, TX USA

[10] St Mary Hosp, Mayo Fdn, Div Cardiol, Rochester, MN USA

关键词: atrial fibrillation;    catheter ablation;    supraventricular;    radiofrequency;    pulmonary vein;   

DOI  :  10.1016/j.jacc.2009.02.022

来源: Elsevier

【 摘 要 】

Objectives The purpose of this study was to provide a systematic multicenter survey on the incidence and causes of death occurring in the setting of or as a consequence of catheter ablation (CA) of atrial fibrillation (AF). Background CA of AF is considered to be generally safe. However, serious complications, including death, have been reported. Methods Using a retrospective case series, data relevant to the incidence and cause of intra- and post-procedural death occurring in patients undergoing CA of AF between 1995 and 2006 were collected from 162 of 546 identified centers worldwide. Results Thirty-two deaths (0.98 per 1,000 patients) were reported during 45,115 procedures in 32,569 patients. Causes of deaths included tamponade in 8 patients (1 later than 30 days), stroke in 5 patients (2 later than 30 days), atrioesophageal fistula in 5 patients, and massive pneumonia in 2 patients. Myocardial infarction, intractable torsades de pointes, septicemia, sudden respiratory arrest, extrapericardial pulmonary vein (PV) perforation, occlusion of both lateral PVs, hemothorax, and anaphylaxis were reported to be responsible for 1 death each, while asphyxia from tracheal compression secondary to subclavian hematoma, intracranial bleeding, acute respiratory distress syndrome, and esophageal perforation from an intraoperative transesophageal echocardiographic probe were causes of 1 late death each. Conclusions Death is a complication of CA of AF, occurring in 1 of 1,000 patients. Knowledge of possible precipitating causes is key to operators and needs to be considered during decision making with patients. (J Am Coll Cardiol 2009; 53: 1798-803) (C) 2009 by the American College of Cardiology Foundation

【 授权许可】

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