Cardiometabolic-Based Chronic Disease, Addressing Knowledge and Clinical Practice Gaps JACC State-of-the-Art Review

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

卷:75

Review

Mechanick, Jeffrey I.¹  Farkouh, Michael E.^2,3  Newman, Jonathan D.^4,5  Garvey, W. Timothy^6,7,8 

[1] Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, Marie Josee & Henry R Kravis Ctr Cardiovasc Hlth, New York, NY 10029 USA

[2] Univ Toronto, Peter Munk Cardiac Ctr, Toronto, ON, Canada

[3] Univ Toronto, Heart & Stroke Richard Lewar Ctr, Toronto, ON, Canada

[4] NYU, Med Ctr, Dept Med, Div Cardiol, New York, NY 10016 USA

[5] NYU, Med Ctr, Dept Med, Ctr Prevent Cardiovasc Dis, New York, NY 10016 USA

[6] Univ Alabama Birmingham, Dept Nutr Sci, Birmingham, AL 35294 USA

[7] Univ Alabama Birmingham, Diabet Res Ctr, Birmingham, AL USA

[8] Birmingham VA Med Ctr, Geriatr Res Educ & Clin Ctr, Birmingham, AL USA

关键词: adipokines;    adiposity;    atherosclerosis;    atrial fibrillation;    cardiometabolic;    cardiomyopathy;    cardiovascular;    chronic disease;    dysglycemia;    health;    insulin;    obesity;    resistance;    type 2 diabetes;   

DOI  :  10.1016/j.jacc.2019.11.046

来源: Elsevier

【 摘 要 】

In the second part of this JACC State-of-the-Art Review, an early and sustainable preventive care plan is described for cardiometabolic-based chronic disease. This plan can improve cardiometabolic health by targeting early mechanistic events to decrease the risk for certain cardiovascular diseases (e.g., coronary heart disease, heart failure, and atrial fibrillation). Included are various prevention modalities, intensive lifestyle interventions, pharmacotherapy and cardiovascular outcome trial evidence, and bariatric/metabolic procedures. A tactical approach of implementing published clinical practice guidelines/algorithms for early behavioral, adiposity, and dysglycemia targeting is emphasized, as well as relevant educational and research implications. (C) 2020 by the American College of Cardiology Foundation.

【 授权许可】

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