Assessment of Myocardial Fibrosis With Cardiovascular Magnetic Resonance

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

卷:57

Review

Mewton, Nathan²  Croisille, Pierre²  Bluemke, David³  Lima, Joao A. C.¹ 

[1] Johns Hopkins Univ, Dept Med, Div Cardiol, Baltimore, MD 21287 USA

[2] Hosp Civils Lyon, Hop Cardiovasc Louis Pradel, Dept Radiol, Lyon, France

[3] Natl Inst Biomed Imaging & Bioengn, NIH, Ctr Clin, Bethesda, MD USA

关键词: cardiac magnetic resonance;    late gadolinium enhancement;    myocardial fibrosis;    T1 mapping;   

DOI  :  10.1016/j.jacc.2010.11.013

来源: Elsevier

【 摘 要 】

Diffuse interstitial or replacement myocardial fibrosis is a common feature of a broad variety of cardiomyopathies. Myocardial fibrosis leads to impaired cardiac diastolic and systolic function and is related to adverse cardiovascular events. Cardiovascular magnetic resonance (CMR) may uniquely characterize the extent of replacement fibrosis and may have prognostic value in various cardiomyopathies. Myocardial longitudinal relaxation time mapping is an emerging technique that could improve CMR's diagnostic accuracy, especially for interstitial diffuse myocardial fibrosis. As such, CMR could be integrated in the monitoring and therapeutic management of a large number of patients. This review summarizes the advantages and limitations of CMR for the assessment of myocardial fibrosis. (J Am Coll Cardiol 2011; 57: 891-903) (C) 2011 by the American College of Cardiology Foundation

【 授权许可】

Free