Ending Gender Inequality in Cardiovascular Clinical Trial Leadership JACC Review Topic of the Week

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

卷:77

Review

Van Spall, Harriette G. C.^1,2,3  Lala, Anuradha⁴  Deering, Thomas F.⁵  Casadei, Barbara⁶  Zannad, Faiez^7,8  Kaul, Padma⁹  Mehran, Roxana¹⁰  Pearson, Gail D.¹¹  Shah, Monica R.¹²  Gulati, Martha¹³  Grines, Cindy¹⁴  Volgman, Annabelle Santos¹⁵  Revkin, James H.¹⁶  Pina, Ileana¹⁷  Lam, Carolyn S. P.^18,19  Hochman, Judith S.²⁰  Simon, Tabassome²¹  Walsh, Mary N.²²  Bozkurt, Biykem^23,24 

[1] McMaster Univ, Dept Med, 20 Copeland Ave,David Braley Res Bldg, Hamilton, ON L8L 0A3, Canada

[2] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada

[3] Populat Hlth Res Inst, Hamilton, ON, Canada

[4] Icahn Sch Med Mt Sinai, Zena & Michael Wiener Cardiovasc Inst, New York, NY 10029 USA

[5] Med Coll Georgia, Piedmont Heart Inst, Atlanta, GA USA

[6] Oxford Univ Hosp NHS Trust, NIHR Oxford Biomed Res Ctr, Div Cardiovasc Med, Oxford, England

[7] Univ Lorraine, INSERM, Nancy, France

[8] CHRU Nancy, Nancy, France

[9] Univ Alberta, Dept Med, Edmonton, AB, Canada

[10] Mt Sinai Hosp, Icahn Sch Med, New York, NY 10029 USA

[11] NHLBI, NIH, Bldg 10, Bethesda, MD 20892 USA

[12] IQVIA, Durham, NC USA

[13] Univ Arizona, Phoenix, AZ USA

[14] Northside Hosp Cardiovasc Inst, Atlanta, GA USA

[15] Rush Univ, Div Cardiol, Chicago, IL 60612 USA

[16] Pfizer Inc, New York, NY USA

[17] Wayne State Univ, Dept Med, Detroit, MI 48202 USA

[18] Natl Heart Ctr Singapore, Singapore, Singapore

[19] Duke Natl Univ Singapore, Singapore, Singapore

[20] NYU, Langone Hlth, Dept Med, New York, NY USA

[21] Sorbonne Univ, AP HP, Dept Clin Pharmacol & Clin Res Platform East Pari, Paris, France

[22] St Vincent Heart Ctr, Indianapolis, IN USA

[23] Baylor Coll Med, Michael E DeBakey Vet Affairs Med Ctr, Houston, TX 77030 USA

[24] Baylor Coll Med, Cardiovasc Inst, Winters Ctr Heart Failure Res, Cardiol, Houston, TX 77030 USA

关键词: disparities;    equity;    gender;    leadership;    principal investigator;    steering committee;    clinical trial;   

DOI  :  10.1016/j.jacc.2021.04.038

来源: Elsevier

【 摘 要 】

Women are under-represented as leaders of cardiovascular randomized controlled trials, representing 1 in 10 lead authors of cardiovascular trials published in high-impact journals. Although the proportion of cardiovascular specialists who are women has increased in recent years, the proportion of cardiovascular clinical trialists who are women has not. This gap, underpinned by systemic sexism, has not been adequately addressed. The benefits of diverse randomized controlled trial leadership extend to patients and professionals. In this position statement, we present strategies adopted by some organizations to end gender inequality in research leadership. We offer an actionable roadmap for early-career researchers, scientists, academic institutions, professional societies, trial sponsors, and journals to follow, with the goal of harnessing the strength of women and under-represented groups as research leaders and facilitating a just culture in the cardiovascular clinical trial enterprise. (J Am Coll Cardiol 2021;77:2960-72) (c) 2021 by the American College of Cardiology Foundation.

【 授权许可】

Free