N-Arylation of carbazole by microwave-assisted ligand-free catalytic CuI reaction

TETRAHEDRON

卷:67

Article

Kwon, Jae Kwan¹  Cho, Joong Hyun¹  Ryu, Young-Sil¹  Oh, Se Hwan¹  Yum, Eul Kgun¹ 

[1] Chungnam Natl Univ, Dept Chem, Taejon 305764, South Korea

关键词: Carbazole;    Microwave;    N-Arylation;    Catalytic;    CuI;   

DOI  :  10.1016/j.tet.2011.05.022

来源: Elsevier

【 摘 要 】

N-Arylation of carbazole has been achieved in high yields within 1 h using a microwave-assisted catalytic CuI reaction with no organic ligand. The N-arylation can be performed by various arylhalides, such as phenyl, pyridine, thiophene, and thiazole moieties. Specifically, N-arylated bromocarbazoles were converted into useful synthetic intermediates for functionalized carbazole materials. (C) 2011 Elsevier Ltd. All rights reserved.

【 授权许可】

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