Advances in the cobalt-catalysed Pauson-Khand reaction: Development of a sulfide-promoted, microwave-assisted protocol

TETRAHEDRON

卷:78

Article

Cochrane, Alison R.¹  Kerr, William J.¹  Paterson, Laura C.¹  Pearson, Colin M.¹  Shaw, Paul¹ 

[1] Univ Strathclyde, Dept Pure & Appl Chem, 295 Cathedral St, Glasgow G1 1XL, Lanark, Scotland

关键词: Catalysis;    Cobalt;    Pauson-Khand;   

DOI  :  10.1016/j.tet.2020.131805

来源: Elsevier

【 摘 要 】

The development of a sulfide-promoted, microwave-assisted Pauson-Khand reaction has enabled the formation of fused cyclopentenones using sub-stoichiometric quantities of a cobalt mediator over rapid reaction times and with no requirement for an external source of toxic carbon monoxide gas. This protocol displays applicability to both intra- and intermolecular Pauson-Khand reaction examples. (C) 2020 Elsevier Ltd. All rights reserved.

【 授权许可】

Free