Synthesis of cyclic dienamide using ruthenium-catalyzed ring-closing metathesis of ene-ynamide

TETRAHEDRON

卷:62

Article

Mori, M ; Wakamatsu, H ; Saito, N ; Sato, Y ; Narita, R ; Fujita, R

关键词: ene-ynamide;    dienamide;    enyne metathesis;    indole;    quinoline;    ethylene;   

DOI  :  10.1016/j.tet.2005.11.083

来源: Elsevier

【 摘 要 】

Ring-closing metathesis of ene-ynamide, which has alkene and ynamide moieties in a molecule, using a second-generation ruthenium carbene complex produced nitrogen-containing heterocycles, which have a dienamide moiety, in high yields. Diels-Alder reaction of the cyclized product with dienophile proceeded smoothly to give an indole or quinoline derivative in high yield. (c) 2006 Elsevier Ltd. All rights reserved.

【 授权许可】

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