Energising the E-factor: The E+-factor

TETRAHEDRON

卷:75

Article

Tieves, Florian¹  Tonin, Fabio¹  Fernandez-Fueyo, Elena¹  Robbins, John M.²  Bommarius, Bettina²  Bommarius, Andreas S.^2,4  Alcalde, Miguel³  Hollmann, Frank¹ 

[1] Delft Univ Technol, Dept Biotechnol, Maasweg 9, NL-2629 HZ Delft, Netherlands

[2] Georgia Inst Technol, Sch Chem & Biomol Engn, 950 Atlantic Dr, Atlanta, GA 30332 USA

[3] CSIC, Dept Biocatalysis, Inst Catalysis, E-28049 Madrid, Spain

[4] Georgia Inst Technol, Sch Chem & Biochem, 901 Atlantic Dr NW, Atlanta, GA 30332 USA

关键词: E-factor;    Green chemistry;    Peroxygenases;    Oxyfunctionalisation chemistry;    Biocatalysis;   

DOI  :  10.1016/j.tet.2019.01.065

来源: Elsevier

【 摘 要 】

The E-factor has become an important measure for the environmental impact of (bio)chemical reactions, However, summing up the obvious wastes generated in the laboratory neglects energy-related wastes (mostly greenhouse gases) which are generated elsewhere. To estimate these wastes, we propose to extend the E-factor by an energy-term (E+-factor). At the example of a lab-scale enzyme fermentation, we demonstrate that the E+-factor can constitute a multiple of the classical E-factor and therefore must not be neglected striving for a holistic estimation of the environmental impact. (C) 2019 The Authors. Published by Elsevier Ltd.

【 授权许可】

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