C-S bond formation catalyzed by N-heterocylic carbene palladium phosphine complexes

TETRAHEDRON

卷:66

Article

Fu, Ching-Feng¹  Liu, Yi-Hung¹  Peng, Shei-Ming¹  Liu, Shiuh-Tzung¹ 

[1] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan

关键词: Palladium;    N-Heterocyclic carbene;    C-S coupling;    Sulfide;   

DOI  :  10.1016/j.tet.2010.01.081

来源: Elsevier

【 摘 要 】

N-Heterocyclic carbenes (NHCs) are known to be useful ligands for palladium-complex catalysis It was found that [(NHC)Pd(PPh3)Cl-2] is an effective pre-catalyst in Pd-catalyzed C-S cross coupling reactions to produce the functionalized sulfides in excellent yields The turn over frequency (TOF) for the coupling of p-CH3C6H4Bi with p-CH3C6H4SH reaches to 6 25 (mol Of product) (mole of catalyst)(-1) h(-1) (C) 2010 Elsevier Ltd All rights reserved

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