Fabric phase sorptive extraction for specific migration analysis of oligomers from biopolymers

TALANTA

卷:233

Article

Ubeda, Sara¹  Aznar, Margarita¹  Nerin, Cristina¹  Kabir, Abuzar² 

[1] Univ Zaragoza, Dept Analyt Chem, EINA, I3A, Madre de Lune 3, Zaragoza 50018, Spain

[2] Florida Int Univ, Dept Chem & Biochem, 11200 SW 8th St, Miami, FL 33199 USA

关键词: Oligomers;    Migration;    NIAS;    FPSE;    Food packaging;    Biopolymer;   

DOI  :  10.1016/j.talanta.2021.122603

来源: Elsevier

【 摘 要 】

Oligomers are potential migrants from polymers or biopolymers intended to food packaging and they have to be under control. In order to comply with European regulation 10/2011, their concentration in migration must be below 0.01 mu g g(-1). In this work, fabric phase sorptive extraction (FPSE) was explored as an effective method for extraction and pre-concentration of oligomers migrated from a blend PLA-polyester material. Both food simulant B (3% acetic acid) and juice, as real food, were used for migration experiments. The parameters of FPSE were optimized and the analysis was done by UHPLC-QTOF and UHPLC-QqQ. A total of 21 oligomers were identified, 9 of them coming from PLA and 12 oligomers from the polyester part. These oligomers were formed by adipic acid (AA), phthalic acid (PA) and/or butanediol (BD), ten were cyclic and 11 were linear molecules. Using the optimized FPSE procedure in 3% acetic acid as food simulant, it was possible to identify 3 new compounds that were not detected by direct injection of the simulant into UHPLC-QTOF. In addition, 2 extra compounds, cyclic PA-BD4-AA(3) and cyclic PA(2)-BD3-AA, were only identified in juice samples after FPSE extraction. Besides, in order to quantify the compounds identified, an isolation procedure for PLA oligomers was carried out. Two oligomers were isolated: cyclic (LA)(6) and linear HO-(LA)(4)-H, both with a purity higher than 90% (LA: lactic acid). The highest concentration value was found for the cyclic oligomer [AA-BD](2), that showed 22.63 mu g g(-1) in 3% acetic acid and 19.64 mu g g(-1) in juice. The concentration of the total amount of remaining oligomers was below 7.56 mu g g(-1) in 3% acetic acid as well as in juice.

【 授权许可】

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