Detection of trace levels of lead in aqueous liquids using extractive electrospray ionization tandem mass spectrometry

TALANTA

卷:98

Article

Liu, Chunxiao²  Zhang, Xinglei¹  Xiao, Saijin¹  Jia, Bin¹  Cui, Shasha^1,3  Shi, Jianbo²  Xu, Ning¹  Xie, Xi⁴  Gu, Haiwei¹  Chen, Huanwen¹ 

[1] E China Inst Technol, Jiangxi Key Lab Mass Spectrometry & Instrumentat, Nanchang 330013, Jiangxi, Peoples R China

[2] Chinese Acad Sci, State Key Lab Environm Chem & Ecotoxicol, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China

[3] Beijing Entry Exit Inspect & Quarantine Bur, Beijing 100026, Peoples R China

[4] ACCA21, Beijing 100038, Peoples R China

关键词: Extractive electrospray ionization;    Ambient mass spectrometry;    Tandem mass spectrometry;    Lead;    Beverage;   

DOI  :  10.1016/j.talanta.2012.06.048

来源: Elsevier

【 摘 要 】

A sensitive approach, based on semi-quantitative measurement of the characteristic fragments in multistage extractive electrospray ionization mass spectrometry (EESI-MSn), was developed for fast detection of trace levels of lead in aqueous liquids including mineral water, lake water, tap water, energy drinks, soft drinks, beer, orange juice, and tea. A disodium ethylene-diamine-tetraacetic acid (EDTA) aqueous solution was electrosprayed to produce negatively charged primary ions which then intersected the neutral sample plume to generate anions of EDTA-Pb(II) complexes. The charged EDTA-Pb(II) complexes were characterized with multistage collision induced dissociation (CID) experiments. The limit of detection (LOD) using EESI-MS3 was estimated to be at the level of 10(-13) g/mL for directly detecting lead in many of these samples. The linear dynamic range was higher than 2 orders of magnitude. A single sample analysis could be completed within 2 min with reasonable semi-quantitative performance, e.g., relative standard deviations (RSDs) for deionized water were 4.6-7.6% during 5 experimental runs (each of them had 10 repeated measurements). Coca-cola and Huiyuan orange juice, representative beverage samples with complex matrices, generated recovery rates of 91.5% and 129%, respectively. Our experimental data demonstrated that EESI-MS is a useful tool for the fast detection of lead in various solutions, and EESI-MS showed promises for fast screening of lead-contaminated aqueous liquid samples. (C) 2012 Elsevier B.V. All rights reserved,

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