Solid-phase extraction microfluidic devices for matrix removal in trace element assay of actinide materials

TALANTA

卷:167

Article

Gao, Jun¹  Manard, Benjamin T.¹  Castro, Alonso¹  Montoya, Dennis P.¹  Xu, Ning¹  Chamberlin, Rebecca M.¹ 

[1] Los Alamos Natl Lab, POB 1663,MS G740, Los Alamos, NM 87545 USA

关键词: Microfluidic device;    Trace impurity;    Plutonium;    Uranium;    Nuclear forensics;   

DOI  :  10.1016/j.talanta.2017.01.080

来源: Elsevier

【 摘 要 】

Advances in sample nebulization and injection technology have significantly reduced the volume of solution required for trace impurity analysis in plutonium and uranium materials. Correspondingly, we have designed and tested a novel chip-based microfluidic platform, containing a 100-mu L, or 20-mu L solid-phase microextraction column, packed by centrifugation, which supports nuclear material mass and solution volume reductions of 90% or more compared to standard methods. Quantitative recovery of 28 trace elements in uranium was demonstrated using a UTEVA chromatographic resin column, and trace element recovery from thorium (a surrogate for plutonium) was similarly demonstrated using anion exchange resin AG MP-1. Of nine materials tested, compatibility of polyvinyl chloride (PVC), polypropylene (PP), and polytetrafluoroethylene (PTFE) chips with the strong nitric acid media was highest. The microcolumns can be incorporated into a variety of devices and systems, and can be loaded with other solid-phase resins for trace element assay in high-purity metals.

【 授权许可】

Free