Boron nitride nanosheets as a platform for fluorescence sensing

TALANTA

卷:174

Article

Zhan, Yuanjin¹  Yan, Jingjing¹  Wu, Mei¹  Guo, Longhua¹  Lin, Zhenyu¹  Qiu, Bin¹  Chen, Guonan¹  Wong, Kwok-yin^2,3 

[1] Fuzhou Univ, MOE Key Lab Anal & Detect Food Safety, Fujian Prov Key Lab Anal & Detect Technol Food Sa, Coll Chem, Fuzhou 350116, Fujian, Peoples R China

[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Kowloon, Hong Kong, Peoples R China

[3] Hong Kong Polytech Univ, State Key Lab Chirosci, Kowloon, Hong Kong, Peoples R China

关键词: Boron nitride nanosheets;    Fluorescence quenching;    Photo-induced electron transfer;    Sensing platform;   

DOI  :  10.1016/j.talanta.2017.06.032

来源: Elsevier

【 摘 要 】

Hexagonal boron nitride nanosheets (BNNS), one kind of inorganic graphene analogue, exhibit high fluorescence quenching ability via the photo-induced electron transfer (PET) and different affinity toward single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). As a proof of concept, the BNNS was first used as a sensing platform for the rapid detection of DNA and small molecules with high sensitivity and selectivity in this study. This strategy is versatile and quick fluorescence sensing of DNA and extensive DNA related analytes such as metal cations and small molecules. Moreover, this strategy might be available for the practical application in future. This work provides an avenue for understanding the interaction between two-dimensional nanomaterials and biomolecules and designing novel sensing strategies for extending the applications of nanomaterials in bioanalysis.

【 授权许可】

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