Reconstructing hydrophobic ZIF-8 crystal into hydrophilic hierarchically-porous nanoflowers as catalyst carrier for nonenzymatic glucose sensing

SENSORS AND ACTUATORS B-CHEMICAL

卷:313

Article

Zhu, Qizhen¹  Hu, Shiyu¹  Zhang, Linqun²  Li, Ying^1,3,4  Carraro, Carlo^3,4  Maboudian, Roya^3,4  Wei, Wei¹  Liu, Anran¹  Zhang, Yuanjian¹  Liu, Songqin¹ 

[1] Southeast Univ, Sch Chem & Chem Engn, Jiangsu Engn Lab Smart Carbon Rich Mat & Device, Nanjing 211189, Peoples R China

[2] Nanjing Normal Univ, Analyt & Testing Ctr, Nanjing 210023, Peoples R China

[3] Univ Calif Berkeley, Berkeley Sensor & Actuator Ctr, Berkeley, CA 94720 USA

[4] Univ Calif Berkeley, Dept Chem & Biomol Engn, Berkeley, CA 94720 USA

关键词: Hydrophilicity;    Hierarchy-pore;    ZIF-8;    Cu nanoparticle;    Non-enzymatic glucose sensor;    Organic weak acid;   

DOI  :  10.1016/j.snb.2020.128031

来源: Elsevier

【 摘 要 】

ZIF-8, a zeolite-type metal-organic framework (MOF), is an effective carrier to support nanocatalysts for applications in the catalysis areas due to its high chemical and thermal stability, and unique structure. The ability to reconstruct the structure of ZIF-8 opens up the potential to enhance its performance in catalysis. In this work, the structure of hydrophobic ZIF-8 crystal is engineered to form hydrophilic hierarchically-porous nanoflowers (HHNs) by using an organic weak acid as etchant. Results reveal that besides imparting hydrophilicity to ZIF-8, the uniform micropores in ZIFs are transformed to mesopores and macropores, which are beneficial to nanoparticle immobilization and electrochemical reactions. After incorporating Cu nanoparticles into the matrix HHNs, the composite Cu@HHNs manifest superior catalytic activities for glucose electro-catalytic oxidation under alkaline media, compared with Cu nanoparticles loaded on untreated ZIF-8. The proposed Cu@HHNs based sensor displays exceptional sensing performances with a linear range of 5 mu M to 3 mM, a detection limit of 1.97 mu M (signal-to-noise ratio (S/N) of 3), a sensitivity of 1594.2 mu A mM(-1) cm(-2), and high selectivity, specificity, and reproducibility. In addition, Cu@HHNs can be utilized for glucose sensing in human blood serum, demonstrating its feasibility toward determination of glucose for practical sample testing.

【 授权许可】

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