Paper-based microfluidic sampling and separation of analytes for potentiometric ion sensing

SENSORS AND ACTUATORS B-CHEMICAL

卷:243

Article

Ding, Jiawang^1,2  He, Ning²  Lisak, Grzegorz^2,3,4  Qin, Wei¹  Bobacka, Johan² 

[1] Chinese Acad Sci, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Environm Proc,YICCA, Yantai 264003, Shandong, Peoples R China

[2] Abo Akad Univ, Johan Gadolin Proc Chem Ctr, Analyt Chem Lab, Biskopsgatan 8, FIN-20500 Turku, Finland

[3] Nanyang Technol Univ, Sch Civil & Environm Engn, 50 Nanyang Ave, Singapore 639798, Singapore

[4] CleanTech, Nanyang Environm & Water Res Inst, 1 Cleantech Loop, Singapore 637141, Singapore

关键词: Potentiometry;    Ion-selective electrodes;    Paper-based sampling;    Paper-based separation;    Chloride;    Salicylate;   

DOI  :  10.1016/j.snb.2016.11.128

来源: Elsevier

【 摘 要 】

This work demonstrates a paper-based microfluidic sampling and separation platform that allows potentiometric sensing of chloride ions in presence of strongly interfering salicylate ions using a solid-contact ion-selective electrode as a detector. The device was composed of two pieces of paper with different shapes and pore sizes. A T shaped filter paper with a pore size of 12-25 was used as the detection zone. A filter paper with a pore size of 2.0 mu m was modified with a complexing agent (Fe3+ and served as the separation zone. The two pieces of the paper were joined together just like a jigsaw. A solid-contact Cl--selective electrode and a reference electrode were gently pressed onto the detection zone to create a direct contact between the electrodes and the solution absorbed in the paper. Utilizing the possibility to form stable complexes between Fe3+ and salicylate, the proposed platform enables the separation of salicylate and detection of chloride. This system offers a convenient platform for both sampling and separation of ions, in which sample pretreatment procedures can be simplified or avoided. (C) 2016 Elsevier B.V. All rights reserved.

【 授权许可】

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