Different signatures between chemically and biologically synthesized nanoparticles in a magnetic sensor: A new technology for multiparametric detection

SENSORS AND ACTUATORS B-CHEMICAL

卷:147

Article

Alphandery, E.¹  Lijeour, L.²  Lalatonne, Y.^3,4  Motte, L.³ 

[1] Univ Paris 06, IMPMC, UMR 7590, CNRS, F-75015 Paris, France

[2] Nanobacterie SARL, F-75016 Paris, France

[3] Univ Paris 13, Lab CSPBAT, F-93017 Bobigny, France

[4] Hop Avicenne, Nucl Med Serv, APHP, F-93009 Bobigny, France

关键词: Magnetosome;    Magnetotactic bacteria;    Biosensor;    Magnetic signature;    Multiparametric immunoassay;    Detectors;    Superparamagnetic nanoparticles;    Maghemite;   

DOI  :  10.1016/j.snb.2010.04.009

来源: Elsevier

【 摘 要 】

A magnetic sensor, called MIAplex (R), has been developed by the company Magnisense. This instrument measures a signal, which is proportional to the second derivative of a magnetization curve. We show that this sensor is able to discriminate between the signature of small superparamagnetic nanoparticles produced chemically and that of larger ferromagnetic nanoparticles produced by magnetotactic bacteria. The reason why this distinction is possible comes from the different magnetization curves of these two types of nanoparticles. These results pave the way for the simultaneous detection of different types of biological molecules or living organisms. (C) 2010 Elsevier B.V. All rights reserved.

【 授权许可】

Free