Wireless fluorimeter for mobile and low cost chemical sensing: A paper based chloride assay

SENSORS AND ACTUATORS B-CHEMICAL

卷:275

Article

Kassal, Petar¹  Steinberg, Matthew D.²  Horak, Ema³  Steinberg, Ivana Murkovic¹ 

[1] Univ Zagreb, Fac Chem Engn & Technol, Marulicev Trg 19, HR-10000 Zagreb, Croatia

[2] GoSense Wireless Ltd, 57A Moorfield Rd, Cambridge CB22 4PP, England

[3] Rudjer Boskovic Inst, Computat Organ Chem & Biochem Grp, Bijenicka Cesta 54, HR-10000 Zagreb, Croatia

关键词: Wireless chemical sensor;    Fluorescent sensor;    Radio-frequency identification;    Paper-based sensor;    Chloride sensor;    Wearable sensor;   

DOI  :  10.1016/j.snb.2018.07.170

来源: Elsevier

【 摘 要 】

Wireless chemical sensors are increasingly finding use as analytical devices in healthcare diagnostics, wearable sensing (sweat analysis) and in the rapidly emerging area of the Sensor Internet of Things (SIoT). In such wireless scenarios, the application of fluorescence-based sensors is lagging behind other types of transduction mechanisms. In this work a new low-cost and highly portable wireless fluorimeter for optical chemical fluorescence intensity measurements is presented (bill-of-materials approximately (sic)20). The fluorimeter is programmed and communicates wirelessly with mobile devices or personal computers by radio-frequency identification (RFID) or near-field communication (NFC). This novel mobile analytical system is highly adaptable for use with different fluorescent sensor chemistries and analyzes. The fluorimeter has been evaluated in the laboratory in two sets of proof-of-concept experiments: firstly fluorimetry in solution, where the fluorescence intensities of fluorescein were recorded, and secondly chloride sensing via a paper-immobilised quinine sulphate fluorescent indicator. The latter represents the first demonstration of wireless (radio-frequency) fluorescence-based chloride sensing. Satisfactory analytical performance was achieved in the entire range of sweat chloride concentrations. The wireless fluorimeter system presented here could make a significant contribution to several emerging areas of mobile chemical sensor research, including wearable sensors for healthcare and sport, mobile point-of-sample diagnostics as well as more generally for the Sensor Internet of Things.

【 授权许可】

Free