A new sensor for determination of nalbuphine using NiO/functional single walled carbon nanotubes nanocomposite and ionic liquid

SENSORS AND ACTUATORS B-CHEMICAL

卷:230

Article

Fouladgar, Masoud¹ 

[1] Islamic Azad Univ, Dept Biochem, Falavarjan Branch, Esfahan, Iran

关键词: Nalbuphine;    NiO;    Carbon nanotubes;    Nanocomposite;    Ionic liquid;   

DOI  :  10.1016/j.snb.2016.02.094

来源: Elsevier

【 摘 要 】

Using a NiO/functional single walled carbon nanotubes nanocomposite incorporated with ionic liquid (IL/NiO/CNT/CPE), we prepared a sensitive and selective sensor for determination of nalbuphine (NA). Nalbuphine is a semi -synthetic analgesic drug. Electrochemical investigations showed that the nanocomposite had catalytic effect on oxidation of nalbuphine and enhanced the oxidation current. This modified electrode had linear dynamic range from 0.2 to 500.0 pinol L-1 NA with detection limit of 0.07 pinol L-1 NA. Selectivity of the sensor has been studied and proposed method has been applied for determination of nalbuphine in biological samples. (C) 2016 Elsevier B.V. All rights reserved.

【 授权许可】

Free