An ISFET-based anion sensor for the potentiometric detection of organic acids in liquid chromatography

SENSORS AND ACTUATORS B-CHEMICAL

卷:67

Article

Poels, I ; Schasfoort, RBM ; Picioreanu, S ; Frank, J ; van Dedem, GWK ; van den Berg, A ; Nagels, LJ

关键词: ISFET;    liquid chromatography;    potentiometric detection;    carboxylic acids;   

DOI  :  10.1016/S0925-4005(00)00531-1

来源: Elsevier

【 摘 要 】

An ion-selective field effect transistor (ISFET) was applied as a potentiometric detector in liquid chromatography (LC) for the determination of organic acids. The ISFET was prepared by coating the gate insulator of the encapsulated transistor with a poly(vinyl chloride) (PVC) matrix membrane containing methyltridodecylammoniumchloride, which enables the detection of organic anions. The ISFET was tested for its applicability as detector for carboxylic acids in ion-exchange and reversed-phase chromatography. Its analytical characteristics were compared to those of a coated-wire electrode (CWE) and of a conventional type of ion-selective electrode (ISE). (C) 2000 Elsevier Science S.A. All rights reserved.

【 授权许可】

Free