Laser activated single-use micropumps

SENSORS AND ACTUATORS B-CHEMICAL

卷:220

Article

Kanakaris, G. P.¹  Fatsis-Kavalopoulos, N.¹  Alexopoulos, L. G.¹ 

[1] Natl Tech Univ Athens, Mech Engn, Athens 15780, Greece

关键词: Microfluidic liquid handling;    Expandable microspheres;    Micropumps;    Optofluidics;    Lab on a Chip;   

DOI  :  10.1016/j.snb.2015.04.101

来源: Elsevier

【 摘 要 】

Lab on Chip technologies have enabled the possibility of novel mu TAS devices (micro Total Analysis System) that could drastically improve health care services for billions of people around the world. However, serious drawbacks that reside in fluid handling technology currently available for these systems often restrict the commercialization of such devices. This work demonstrates a novel fluid handling method as a possible alternative to current micropumping techniques for disposable microfluidic chips. This technology is based on a single use, low cost, thermal micropumping system in which expandable microsphere mixtures are activated by commercial grade laser diodes to achieve flow rates as high as 2.2 mu l/s and total volumes over 160 mu l. With the addition of a volume dependent shut off valve, nanoliter repeatability is realized. Pressure and heat transfer related data are presented. Finally, the possible prospects and limitations of this technology as a core element in unified optofluidic systems are discussed. (C) 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

【 授权许可】

Free