Ventilation rate in adults with a tracheal tube during cardiopulmonary resuscitation: A systematic review

RESUSCITATION

卷:119

Review

Vissers, Gino^1,2  Soar, Jasmeet³  Monsieurs, Koenraad G.^1,2 

[1] Univ Antwerp, Fac Med & Hlth Sci, Antwerp, Belgium

[2] Antwerp Univ Hosp, Dept Emergency Med, Wilrijkstr 10, B-2650 Edegem, Belgium

[3] Southmead Hosp, Dept Anaesthesia & Intens Care Med, Bristol, Avon, England

关键词: Cardiac arrest;    Neurological outcome;    Outcome;    Resuscitation;    ROSC;    Tracheal tube;    Ventilation rate;   

DOI  :  10.1016/j.resuscitation.2017.07.018

来源: Elsevier

【 摘 要 】

Aim: The optimal ventilation rate during cardiopulmonary resuscitation (CPR) with a tracheal tube is unknown. We evaluated whether in adults with cardiac arrest and a secure airway (tracheal tube), a ventilation rate of 10 min(-1), compared to any other rate during CPR, improves outcomes. Methods: A systematic review up to 14 July 2016. We included both adult human and animal studies. A GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach was used to evaluate the quality of evidence for each outcome. Results: We identified one human observational study with 67 patients and ten animal studies (234 pigs and 30 dogs). All studies carried a high risk of bias. All studies evaluated for return of spontaneous circulation (ROSC). Studies showed no improvement in ROSC with a ventilation rate of 10 min-1 compared to any other rate. The evidence for longer-term outcomes such as survival to discharge and survival with favourable neurological outcome was very limited. Conclusion: A ventilation rate recommendation of 10 min-1 during adult CPR with a tracheal tube and no pauses for chest compression is a very weak recommendation based on very low quality evidence. (C) 2017 Elsevier B.V. All rights reserved.

【 授权许可】

Free