Socioeconomic status and subclinical atherosclerosis in older adults

PREVENTIVE MEDICINE

卷:52

Article

Nash, Scott D.¹  Cruickshanks, Karen J.^1,2  Klein, Ronald²  Klein, Barbara E. K.²  Nieto, F. Javier¹  Ryff, Carol D.³  Krantz, Elizabeth M.²  Shubert, Carla R.²  Nondahl, David M.²  Acher, Charles W.⁴ 

[1] Univ Wisconsin, Dept Populat Hlth Sci, Madison, WI 53726 USA

[2] Univ Wisconsin, Dept Ophthalmol & Visual Sci, Madison, WI 53726 USA

[3] Univ Wisconsin, Inst Aging, Madison, WI 53726 USA

[4] Univ Wisconsin, Dept Surg, Madison, WI 53726 USA

关键词: Socioeconomic status;    Intima-media thickness;    Atherosclerosis;    Carotid artery plaque;    Cardiovascular disease;    Life-course epidemiology;   

DOI  :  10.1016/j.ypmed.2010.12.009

来源: Elsevier

【 摘 要 】

Objective. This study investigated the long-term effects of socioeconomic status (SES) on atherosclerosis. Methods. Data from the Epidemiology of Hearing Loss Study and the Beaver Dam Eye Study (Beaver Dam, WI, 1998-2000), were used to examine adult SES (education, household income, and longest-held job) and childhood SES (household density and parental home ownership at age 13) associations with carotid intimamedia thickness (IMT) and carotid plaque in a cohort of 2042 men and women aged 53 to 94 years. Results. For education, income, and occupation (women), those in the lowest SES group had statistically larger age-sex-adjusted IMT than those in the highest SES group (< 12 vs. > 12 years education: 0.92 vs. 0.86 mm respectively, P < 0.0001), (410,000 vs. >$45,000: 0.97 vs. 0.87 mm, P < 0.0001), (operator/fabricator/labor vs. manager/professional: 0.89 vs. 0.82 mm, P < 0.001). Associations were similar using carotid plaque as the outcome. Participants with low levels of both adult and childhood SES measures had age-sex-adjusted IMT greater than those with persistently high levels of SES (0.93 vs. 0.84 mm, P < 0.0001). Conclusions. Measures of SES at two points in the life-span were associated with subclinical atherosclerosis. (C) 2011 Elsevier Inc. All rights reserved.

【 授权许可】

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