Prescription opioid misuse among adolescents and emerging adults in the United States: A scoping review

PREVENTIVE MEDICINE

卷:132

Review

Bonar, Erin E.^1,2,3  Coughlin, Lara^1,2  Roche, Jessica S.^3,4  Philyaw-Kotov, Meredith L.^1,2  Bixler, Emily A.⁵  Sinelnikov, Sergey⁵  Kolosh, Alaina⁵  Cihak, Morgan J.⁵  Cunningham, Rebecca M.^3,4,6  Walton, Maureen A.^1,2,3 

[1] Univ Michigan, Addict Ctr, 4250 Plymouth Rd, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Sch Med, Dept Psychiat, 4250 Plymouth Rd, Ann Arbor, MI 48109 USA

[3] Univ Michigan, Sch Med, Injury Prevent Ctr, 2800 Plymouth Rd,NCRC10-G080, Ann Arbor, MI 48109 USA

[4] Univ Michigan, Sch Med, Dept Emergency Med, 2800 Plymouth Rd,NCRC10-G080, Ann Arbor, MI 48109 USA

[5] Natl Safety Council, 1121 Spring Lake Dr, Itasca, IL 60143 USA

[6] Univ Michigan, Sch Publ Hlth, Dept Hlth Behav & Hlth Educ, 1415 Washington Hts,3790A SPH 1, Ann Arbor, MI 48109 USA

关键词: Prescription opioids;    Opioid misuse;    Opioid abuse;    Adolescents;    Emerging adults;    Scoping review;   

DOI  :  10.1016/j.ypmed.2019.105972

来源: Elsevier

【 摘 要 】

The U.S. opioid epidemic is a critical public health problem. As substance use and misuse typically begin in adolescence and emerging adulthood, there is a critical need for prevention efforts for this key developmental period to disrupt opioid misuse trajectories, reducing morbidity and mortality [e.g., overdose, development of opioid use disorders (OUD)]. This article describes the current state of research focusing on prescription opioid misuse (POM) among adolescents and emerging adults (A/EAs) in the U.S. Given the rapidly changing nature of the opioid epidemic, we applied PRISMA Scoping Review (PRISMA-ScR) guidelines to identify empirical articles published in the past 5 years (January 2013-September 2018) from nine databases examining POM among A/EAs (ages 10-25) in the U.S. Seventy-six articles met our inclusion criteria focusing on POM in the following areas: cross-sectional surveys (n = 60), longitudinal cohort studies (n = 5), objective, non-self-reported data sources (n = 9), and interventions (n = 2). Final charted data elements were organized by methodology and sample, with results tables describing design, sample, interventions (where applicable), outcomes, and limitations. Most studies focused on the epidemiology of POM and risk/protective factors, including demographic (e.g., sex, race), individual (e.g., substance use, mental health), and social (e.g., peer substance use) factors. Despite annual national surveys conducted, longitudinal studies examining markers of initiation and escalation of prescription opioid misuse (e.g., repeated overdoses, time to misuse) are lacking. Importantly, few evidence-based prevention or early intervention programs were identified. Future research should examine longitudinal trajectories of POM, as well as adaptation and implementation of promising prevention approaches.

【 授权许可】

Free