Association between cannabis laws and opioid prescriptions among privately insured adults in the US

PREVENTIVE MEDICINE

卷:125

Article

Raji, Mukaila A.^1,2  Abara, N. Ogechi¹  Salameh, Habeeb³  Westra, Jordan R.⁴  Kuo, Yong-Fang^2,4 

[1] Univ Texas Med Branch, Dept Internal Med, Div Geriatr, 301 Univ Blvd, Galveston, TX 77555 USA

[2] Univ Texas Med Branch, Sealy Ctr Aging, 301 Univ Blvd, Galveston, TX 77555 USA

[3] Univ Texas Med Branch, Dept Internal Med, Div Gastroenterol & Hepatol, Galveston, TX 77555 USA

[4] Univ Texas Med Branch, Off Biostat Prevent Med & Community Hlth, Galveston, TX 77555 USA

关键词: Medical cannabis;    Marijuana;    Opioid;    Prescription;    Commercial insurance;    Cross-sectional;    Cannabis;   

DOI  :  10.1016/j.ypmed.2019.05.012

来源: Elsevier

【 摘 要 】

We examine the association between opioid prescription patterns in privately insured adults and changes in state cannabis laws among five age groups (18-25, 26-35 36-45, 46-55 and 56-64 years). Using the 2016 Clinformatics Data Mart, a nationwide commercial health insurance database, we performed a cross-sectional analysis of two types of opioid prescribing (> 30-day and > 90-day prescriptions) among all adults aged 18-64 based on the stringency of cannabis laws. We found a significant interaction between age and cannabis law on opioid prescriptions. Age-stratified multilevel multivariable analyses showed lower opioid prescription rates in the four younger age groups only in states with medical cannabis laws, when considering both > 30 day and > 90 day opioid use [> 30 day adjusted odds ratio (aOR) = 0.56, in 18-25, aOR = 0.67 in 26-35, aOR = 0.67 in 36-45, and aOR = 0.76 in 46-54 years; > 90 day aOR = 0.56, in 18-25, aOR = 0.68 in 26-35, aOR = 0.69 in 36-45, and aOR = 0.77 in 46-54 years, P < 0.0001 for all]. This association was not significant in the oldest age group of 55-64 years. There was no significant association between opioid prescriptions and other categories of cannabis laws (recreational use and decriminalization) in any of the age groups studied.

【 授权许可】

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