Fit and Strong! Plus: Twelve and eighteen month follow-up results for a comparative effectiveness trial among overweight/obese older adults with osteoarthritis

PREVENTIVE MEDICINE

卷:141

Article

Fitzgibbon, Marian L.^1,4,7  Tussing-Humphreys, Lisa^1,4,5  Schiffer, Linda¹  Smith-Ray, Renae^1,6  Marquez, David X.^1,2,8  DeMott, Andrew D.^1,2  Berbaum, Michael L.¹  Hughes, Susan L.^1,2,3 

[1] Univ Illinois, Inst Hlth Res & Policy, Sch Publ Hlth, 1747 West Roosevelt Rd, Chicago, IL 60608 USA

[2] Univ Illinois, Ctr Res Hlth & Aging, 1747 West Roosevelt Rd, Chicago, IL 60608 USA

[3] Univ Illinois, Div Community Hlth Sci, 1603 West Taylor St, Chicago, IL 60612 USA

[4] Univ Illinois, Ctr Canc, 818 South Wolcott Ave, Chicago, IL 60612 USA

[5] Univ Illinois, Dept Med, 808 South Wood St, Chicago, IL 60612 USA

[6] Walgreen Co, Hlth Analyt Res & Reporting, 102 Wilmot Rd, Deerfield, IL 60015 USA

[7] Univ Illinois, Dept Pediat, 840 South Wood St, Chicago, IL 60612 USA

[8] Univ Illinois, Dept Kinesiol & Nutr, 1919 West Taylor St, Chicago, IL 60612 USA

关键词: Osteoarthritis;    Weight management;    Diet;    Physical activity;    Comparative effectiveness trial;   

DOI  :  10.1016/j.ypmed.2020.106267

来源: Elsevier

【 摘 要 】

This comparative effectiveness trial compared the longer-term effectiveness (12 and 18 months) of the standard Fit & Strong! physical activity program to Fit & Strong! Plus, which combined physical activity and dietary weight loss. Outcomes were weight, diet quality, physical activity, osteoarthritis symptoms, performance measures, and anxiety/depression. In this study, 413 overweight/obese participants with OA, =60 years old and primarily African American, were randomly assigned to Fit & Strong! (F&S!) or Fit & Strong! Plus (F&S! Plus), with outcomes assessed at 2, 6, 12, and 18 months. 356 (86%) participants completed the 18-month visit. Compared with participants randomized to standard F&S!, F&S! Plus participants maintained longer-term benefits at 12 months in weight (mean change +/- SE: -1.7 +/- 0.3 kg for F&S! Plus vs -0.9 +/- 0.3 kg for F&S!, p = 0.049), BMI (-0.6 +/- 0.1 vs -0.3 +/- 0.1 kg/m(2), p = 0.04), waist circumference (-2.7 +/- 0.6 vs -0.4 +/- 0.6 cm, p = 0.004), and lower extremity strength (1.6 +/- 0.2 vs 1.0 +/- 0.2 chair stands, p = 0.046). At 18 months, F&S! Plus participants showed improved lower extremity strength (1.4 +/- 0.2 vs. 0.7 +/- 0.2 chair stands, p = 0.045. African American older adults in the F&S! Plus arm showed sustained modest improvements in weight, waist circumference, and lower extremity strength at 12 months and in lower extremity strength at 18 months compared to F&S!. Implications for the translation of evidence-based programs into community settings to support healthy behaviors in older adults are discussed.

【 授权许可】

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