Allan N. Epstein award: Intracellular signaling and ingestive behaviors

PHYSIOLOGY & BEHAVIOR

卷:100

Article; Proceedings Paper

Daniels, Derek

关键词: Angiotensin;    Body fluid homeostasis;    cAMP;    Drinking;    Food intake;    Inositol trisphosphate;    MAP kinase;    Melanocortin;    Salt intake;    Water intake;   

DOI  :  10.1016/j.physbeh.2010.03.012

来源: Elsevier

【 摘 要 】

Understanding the role of intracellular signaling pathways in ingestive behavior is a challenging problem in behavioral neuroscience. This review summarizes work conducted on two systems with the aim of identifying intracellular events that relate to food and fluid intake. The first set of experiments focused on melanocortin receptors and their ability to signal through members of the mitogen-activated protein (MAP) kinase family. The second set of experiments focused on the role of intracellular signaling pathways in water and saline intakes that are stimulated by angiotensin II (AngII). The initial findings in each line of research have been extended by subsequent research that is discussed in turn. The paper represents an invited review by a symposium, award winner or keynote speaker at the Society for the Study of Ingestive Behavior [SSIB] Annual Meeting in Portland, July 2009. (C) 2010 Elsevier Inc. All rights reserved.

【 授权许可】

Free