Advances in the neurobiological bases for food 'liking' versus 'wanting'

PHYSIOLOGY & BEHAVIOR

卷:136

Article

Castro, D. C.¹  Berridge, K. C.¹ 

[1] Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA

关键词: Nucleus accumbens;    Ventral pallidum;    Hedonic hotspot;    Pleasure;    Parabrachial nucleus;    Optogenetics;    Reward;    Motivation;   

DOI  :  10.1016/j.physbeh.2014.05.022

来源: Elsevier

【 摘 要 】

The neural basis of food sensory pleasure has become an increasingly studied topic in neuroscience and psychology. Progress has been aided by the discovery of localized brain subregions called hedonic hotspots in the early 2000s, which are able to causally amplify positive affective reactions to palatable tastes (liking') in response to particular neurochemical or neurobiological stimulations. Those hedonic mechanisms are at least partly distinct from larger mesocorticolimbic circuitry that generates the incentive motivation to eat (wanting'). In this review, we aim to describe findings on these brain hedonic hotspots, especially in the nucleus accumbens and ventral pallidum, and discuss their role in generating food pleasure and appetite. (C) 2014 Elsevier Inc All rights reserved.

【 授权许可】

Free