Acute exposure to a high-fat diet alters meal patterns and body composition

PHYSIOLOGY & BEHAVIOR

卷:99

Article

Melhorn, Susan J.^1,2  Krause, Eric G.¹  Scott, Karen A.^1,2  Mooney, Marie R.³  Johnson, Jeffrey D.³  Woods, Stephen C.¹  Sakai, Randall R.¹ 

[1] Univ Cincinnati, Coll Med, Dept Psychiat, Cincinnati, OH 45237 USA

[2] Univ Cincinnati, Coll Med, Program Neurosci, Cincinnati, OH 45237 USA

[3] Univ Cincinnati, Dept Biomed Engn, Cincinnati, OH 45221 USA

关键词: Meal patterns;    High-fat diet;    Body weight;    Body composition;   

DOI  :  10.1016/j.physbeh.2009.10.004

来源: Elsevier

【 摘 要 】

Weight gain and adiposity are often attributed to the overconsumption of unbalanced, high-fat diets however, the pattern of consumption can also contribute to associated body weight and compositional changes. The present Study explored the rapid alterations in meal patterns of normal-weight rats given continuous access to high-fat diet and examined body weight and composition changes compared to chow fed controls. Ten Long-Evans rats were implanted with Subcutaneous microchips for meal pattern analysis. Animals were body weight matched and separated into two groups: high-fat or chow fed. Each group was maintained on their assigned diet for nine days and monitored for 22 h each day for meal pattern behavior. Body weight was evaluated every other day, and body composition measures were taken prior and following diet exposure. High-fat fed animals gained more weight and adipose tissue than chow fed controls and displayed a reduced meal frequency and increased meal size. Furthermore, meal size was significantly correlated with the gain of adipose tissue. Together, these results Suggest that consumption of a high-fat diet can rapidly alter meal patterns, which in turn contribute to the development of adiposity. Published by Elsevier Inc.

【 授权许可】

Free