Leptin concentrations in response to acute stress predict subsequent intake of comfort foods

PHYSIOLOGY & BEHAVIOR

卷:107

Article

Tomiyama, A. Janet^1,2  Schamarek, Imke³  Lustig, Robert H.^2,4  Kirschbaum, Clemens³  Puterman, Eli⁵  Havel, Peter J.^6,7  Epel, Elissa S.² 

[1] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90024 USA

[2] UCSF, Ctr Obes Assessment Study & Treatment, San Francisco, CA USA

[3] Dresden Univ, Dept Psychol, Dresden, Germany

[4] UCSF, Dept Pediat, San Francisco, CA USA

[5] UCSF, Dept Psychiat, San Francisco, CA USA

[6] Univ Calif Davis, Dept Mol Biosci, Sch Vet Med, Davis, CA USA

[7] Univ Calif Davis, Dept Nutr, Davis, CA USA

关键词: Stress;    Leptin;    Cortisol;    Eating behavior;    Stress eating;   

DOI  :  10.1016/j.physbeh.2012.04.021

来源: Elsevier

【 摘 要 】

Both animals and humans show a tendency toward eating more comfort food (high fat, sweet food) after acute stress. Such stress eating may be contributing to the obesity epidemic, and it is important to understand the underlying psychobiological mechanisms. Prior investigations have studied what makes individuals eat more after stress; this study investigates what might make individuals eat less. Leptin has been shown to increase following a laboratory stressor, and is known to regulate satiety. This study examined whether leptin reactivity accounts for individual differences in stress eating. To test this, we exposed forty women to standardized acute psychological laboratory stress (Trier Social Stress Test) while blood was sampled repeatedly for measurements of plasma leptin. We then measured food intake after the stressor. Increasing leptin during the stressor predicted lower intake of comfort food. These initial findings suggest that acute changes in leptin may be one of the factors modulating down the consumption of comfort food following stress. (C) 2012 Elsevier Inc. All rights reserved.

【 授权许可】

Free