Modulation of excitatory synaptic coupling facilitates synchronization and complex dynamics in a nonlinear model of neuronal dynamics

NEUROCOMPUTING

卷:52-4

Article

Breakspear, M ; Terry, JR ; Friston, KJ

关键词: synchronization;    intermittency;    neuromodulation;   

DOI  :  10.1016/S0925-2312(02)00740-3

来源: Elsevier

【 摘 要 】

We study dynamical synchronization in a model of a neural system constituted by local networks of densely interconnected excitatory and inhibitory neurons. Neural dynamics are determined by voltage- and ligand-gated ion channels. Coupling between the local networks is introduced via sparse excitatory connectivity. With modulation of this long-range synaptic coupling the system undergoes a transition from independent oscillations to chaotic synchronization. Between these states exists a 'weakly' stable state with epochs of synchronization and complex intermittent desynchronization. This may facilitate adaptive brain function by engendering a diverse repertoire of dynamics and contribute to the genesis of complexity in the EEG. (C) 2003 Elsevier Science B.V. All rights reserved.

【 授权许可】

Free