Assessment of microplastic-sorbed contaminant bioavailability through analysis of biomarker gene expression in larval zebrafish

MARINE POLLUTION BULLETIN

卷:116

Article

Sleight, Victoria A.^1,2,3  Bakir, Adil^1,4,5  Thompson, Richard C.¹  Henry, Theodore B.^1,3,6,7 

[1] Univ Plymouth, Marine Biol & Ecol Res Ctr, Sch Marine Sci & Engn, Plymouth PL4 8AA, Devon, England

[2] NERC, British Antarcic Survey, High Cross,Madingley Rd, Cambridge CB3 0ET, England

[3] Heriot Watt Univ, Sch Energy Geosci Infrastruct & Soc, Inst Life & Earth Sci, Edinburgh EH14 4AS, Midlothian, Scotland

[4] Univ Plymouth, Sch Geog Earth & Environm Sci, Petr & Environm Geochem Grp, Plymouth PL4 8AA, Devon, England

[5] Univ Portsmouth, Sch Earth & Environm Sci, Burnaby Rd, Portsmouth PO1 3QL, Hants, England

[6] Univ Tennessee, Ctr Environm Biotechnol, Knoxville, TN 37996 USA

[7] Univ Tennessee, Dept Forestry Wildlife & Fisheries, Knoxville, TN 37996 USA

关键词: Danio rerio;    Microplastics;    Phenanthrene;    17 alpha-ethinylestradiol;    Sorption;    Bioavailability;   

DOI  :  10.1016/j.marpolbul.2016.12.055

来源: Elsevier

【 摘 要 】

Microplastics (MPs) are prevalent in marine ecosystems. Because toxicants (termed here co-contaminants) can sorb to MPs, there is potential for MPs to alter co-contaminant bioavailability. Our objective was to demonstrate sorption of two co-contaminants with different physicochemistries Iphenanthrene (Phe), log(10)K(ow) = 4.57; and 17 alpha-ethinylestradiol (EE2), log(10)K(ow) = 3.67] to MPs; and assess whether co-contaminant bioavailability was increased after MP settlement. Bioavailability was indicated by gene expression in larval zebrafish. Both Phe and EE2 sorbed to MPs, which reduced bioavailability by a maximum of 33% and 48% respectively. Sorption occurred, but was not consistent with predictions based on co-contaminant physicochemistry (Phe having higher log(10)K(ow) was expected to have higher sorption). Contaminated MPs settled to the bottom of the exposures did not lead to increased bioavailability of Phe or EE2. Phe was 48% more bioavailable than predicted by a linear sorption model, organism-based measurements therefore contribute unique insight into MP co-contaminant bioavailability. (C) 2016 The Authors. Published by Elsevier Ltd.

【 授权许可】

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