The nature and timing of social deficits in child and adolescent offspring of parents with schizophrenia: Preliminary evidence for precursors of negative symptoms?

SCHIZOPHRENIA RESEARCH

卷:159

Article

Horton, Leslie E.¹  Smith, Ashley A.¹  Haas, Gretchen L.^1,2 

[1] Univ Pittsburgh, Med Ctr, Western Psychiat Inst & Clin, Dept Psychiat, Pittsburgh, PA 15213 USA

[2] VA Pittsburgh Healthcare Syst, Pittsburgh, PA USA

关键词: High-risk;    Schizophrenia;    Social skills;    Premorbid adjustment;    Social anhedonia;    Social amotivation;    Negative symptoms;   

DOI  :  10.1016/j.schres.2014.07.007

来源: Elsevier

【 摘 要 】

Children with social dysfunction and a first-degree relative with schizophrenia are at elevated risk for schizophrenia; however, the nature of this dysfunction is unclear. It was hypothesized that familial high-risk (HR) children and adolescents (n = 17) would have social skill deficits relative to healthy controls (HC; n = 35). HR participants had a bimodal distribution of social skill scores (47% excellent; 53% poor). HR participants had worse social skills, assertion and empathy scores, suggesting possible developmental precursors to the social amotivation domain of negative symptoms. Characterizing HR children's social deficits could assist identification of those at risk for schizophrenia. (C) 2014 Elsevier B. V. All rights reserved.

【 授权许可】

Free