Effects of a lifestyle intervention on psychosocial well-being of severe mentally ill residential patients: ELIPS, a cluster randomized controlled pragmatic trial

SCHIZOPHRENIA RESEARCH

卷:199

Article

Stiekema, Annemarie P. M.^1,2  Looijmans, Anne^3,4  van der Meer, Lisette^1,4,5  Bruggeman, Richard^4,6  Schoevers, Robert A.⁶  Corpeleijn, Eva³  Jorg, Frederike^4,7 

[1] Lentis Psychiat Inst, Dept Rehabil, Zuidlaren, Netherlands

[2] Maastricht Univ, Fac Hlth Med & Life Sci, Sch Mental Hlth & Neurosci, Dept Psychiat & Neuropsychol,Med Ctr, Maastricht, Netherlands

[3] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands

[4] Univ Groningen, Univ Med Ctr Groningen, Rob Giel Res Ctr, Groningen, Netherlands

[5] Univ Groningen, Univ Med Ctr Groningen, Dept Neurosci, Groningen, Netherlands

[6] Univ Groningen, Univ Med Ctr Groningen, Univ Ctr Psychiat, Groningen, Netherlands

[7] Friesland Mental Hlth Serv, Res Dept, Leeuwarden, Netherlands

关键词: Diet;    Physical activity;    Depression;    Quality of life;    Psychotic symptoms;    Social functioning;   

DOI  :  10.1016/j.schres.2018.02.053

来源: Elsevier

【 摘 要 】

Large studies investigating the psychosocial effects of lifestyle interventions in patients with a severe mental illness (SMI) are scarce, especially in residential patients. This large, randomized controlled, multicentre pragmatic trial assessed the psychosocial effects of a combined diet-and-exercise lifestyle intervention targeting the obesogenic environment of SMI residential patients. Twenty-nine sheltered and clinical care teams were randomized into intervention (n = 15) or control (n = 14) arm. Team tailored diet-and-exercise lifestyle plans were set up to change the obesogenic environment into a healthier setting, and team members were trained in supporting patients to make healthier choices. The control group received care-as-usual. The Calgary Depression Scale for Schizophrenia (CDSS), Positive and Negative Syndrome Scale (PANSS), Health of the Nation Outcome Scales (HoNOS) and the Manchester Short Assessment of Quality of Life (MANSA) were assessed at baseline and after three and twelve months. Data were available for 384 intervention and 386 control patients (48.6 +/- 12.5 years old, 62.7% males, 73.7% psychotic disorder). Linear mixed model analysis showed no psychosocial improvements in the intervention group compared to care-as-usual; the intervention group showed a slightly reduced quality of life (overall) and a small increase in depressive symptoms (clinical care facilities) and psychotic symptoms (sheltered facilities). This may be due to difficulties with implementation, the intervention not being specifically designed for improvements in mental well-being, or the small change approach, which may take longer to reach an effect. Further research might elucidate what type of lifestyle intervention under what circumstances positively affects psychosocial outcomes in this population. (c) 2018 Elsevier B.V. All rights reserved.

【 授权许可】

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