The aprosody of schizophrenia: Computationally derived acoustic phonetic underpinnings of monotone speech

SCHIZOPHRENIA RESEARCH

卷:197

Article

Compton, Michael T.¹  Lunden, Anya²  Cleary, Sean D.³  Pauselli, Luca¹  Alolayan, Yazeed⁴  Halpern, Brooke⁵  Broussard, Beth⁵  Crisafio, Anthony⁶  Capulong, Leslie⁵  Balducci, Pierfrancesco Maria⁷  Bernardini, Francesco⁸  Covington, Michael A.⁹ 

[1] Columbia Univ Coll Phys & Surg, Dept Psychiat, 722 W 168th St, New York, NY 10032 USA

[2] Coll William & Mary, Dept English, Linguist Program, Williamsburg, VA USA

[3] George Washington Univ, Milken Inst, Sch Publ Hlth, Dept Epidemiol & Biostat, Washington, DC USA

[4] Case Western Reserve Univ, Dept Neurol, Cleveland, OH 44106 USA

[5] Lenox Hill Hosp, New York, NY 10021 USA

[6] George Washington Univ, Sch Med & Hlth Sci, Washington, DC 20052 USA

[7] Univ Perugia, Dept Med, Sect Psychiat, Perugia, Italy

[8] Univ Libre Bruxelles, Erasme Hosp, Dept Psychiat, Anderlecht, Belgium

[9] Univ Georgia, Inst Artificial Intelligence, Athens, GA 30602 USA

关键词: Acoustic resonance;    Aprosody;    Linguistics;    Negative symptoms;    Phonetics;    Phonology;    Psychosis;    Schizophrenia;   

DOI  :  10.1016/j.schres.2018.01.007

来源: Elsevier

【 摘 要 】

Objective: Acoustic phonetic methods are useful in examining some symptoms of schizophrenia; we used such methods to understand the underpinnings of aprosody. We hypothesized that, compared to controls and patients without clinically rated aprosody, patients with aprosody would exhibit reduced variability in: pitch (F0), jaw/mouth opening and tongue height (formant F1), tongue front/back position and/or lip rounding (formant F2), and intensity/loudness. Methods: Audiorecorded speech was obtained from 98 patients (including 25 with clinically rated aprosody and 29 without) and 102 unaffected controls using five tasks: one describing a drawing, two based on spontaneous speech elicited through a question (Tasks 2 and 3), and two based on reading prose excerpts (Tasks 4 and 5). We compared groups on variation in pitch (F0), formant F1 and F2, and intensity/loudness. Results: Regarding pitch variation, patients with aprosody differed significantly from controls in Task 5 in both unadjusted tests and those adjusted for sociodemographics. For the standard deviation (SD) of F1, no significant differences were found in adjusted tests. Regarding SD of F2, patients with aprosody had lower values than controls in Task 3, 4, and 5. For variation in intensity/loudness, patients with aprosody had lower values than patients without aprosody and controls across the five tasks. Conclusions: Findings could represent a step toward developing new methods for measuring and tracking the severity of this specific negative symptom using acoustic phonetic parameters; such work is relevant to other psychiatric and neurological disorders. (C) 2018 Elsevier B.V. All rights reserved.

【 授权许可】

Free