Supramolecular hydrogels with multi-cylindrical lamellar bilayers: Swelling-induced contraction and anisotropic molecular diffusion

POLYMER

卷:128

Article

Mito, Kei¹  Haque, Md. Anamul^2,3  Nakajima, Tasuku^2,4  Uchiumi, Maki⁵  Kurokawa, Takayuki^2,4  Nonoyama, Takayuki^2,4  Gong, Jian Ping^2,4 

[1] Hokkaido Univ, Grad Sch Life Sci, Kita Ku, N10W8, Sapporo, Hokkaido 0600810, Japan

[2] Hokkaido Univ, Fac Adv Life Sci, Kita Ku, N21W11, Sapporo, Hokkaido 0010021, Japan

[3] Univ Dhaka, Dept Chem, Dhaka 1000, Bangladesh

[4] Hokkaido Univ, Global Inst Collaborat Res & Educ, Global Stn Soft Matter, Sapporo, Hokkaido, Japan

[5] Hokkaido Univ, Sch Sci, Kita Ku, N10W8, Sapporo, Hokkaido 0600810, Japan

关键词: Gel;    Bilayer;    Anisotropy;    Swelling;    Diffusion;   

DOI  :  10.1016/j.polymer.2017.01.038

来源: Elsevier

【 摘 要 】

Novel, supramolecular, anisotropic hydrogels (called MC-PDGI gels) are presented in this study. These MC-PDGI gels consist of multi-cylindrical lipid bilayers aligned in a uniaxial manner and embedded in a soft hydrogel matrix. The bilayers and the hydrogel interact weakly due to hydrogen bonding. These MC-PDGI gels swell after exposure to water, which causes their volume and diameter to increase while simultaneously causing their length to decrease. This anisotropic swelling-induced contraction behavior is the result of competition between the isotropic elasticity of the hydrogel matrix and the interfacial tension of the lipid bilayers. Moreover, the MC-PDGI gels exhibit unique quasi one-dimensional diffusion behavior owing to the difficulty of molecular penetration through the multi-layered lipid bilayers. These materials would be useful for prolonged drug release or as an actuator. (C) 2017 Elsevier Ltd. All rights reserved.

【 授权许可】

Free