Noradrenergic control of the bed nucleus of the stria terminalis in stress and reward

NEUROPHARMACOLOGY

卷:70

Review

Flavin, Stephanie A.^1,2,3  Winder, Danny G.^1,2,3 

[1] Vanderbilt Univ, Sch Med, Dept Mol Physiol & Biophys, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Sch Med, JE Kennedy Ctr Res Human Dev, Nashville, TN 37232 USA

[3] Vanderbilt Univ, Sch Med, Vanderbilt Brain Inst, Neurosci Program Substance Abuse, Nashville, TN 37232 USA

关键词: Stress;    Addiction;    Norepinephrine;    Extended amygdala;    Bed nucleus of the stria terminalis;    Central nucleus of the amygdala;    Stress-induced reinstatement;   

DOI  :  10.1016/j.neuropharm.2013.02.013

来源: Elsevier

【 摘 要 】

The bed nucleus of the stria terminalis (BNST) is a group of inter-connected subnuclei that play critical roles in stress reward interactions. An interesting feature of this brain region is the massive noradrenergic input that it receives. Important roles for norepinephrine in this region have been documented in a number of stress and reward related behaviors. This work has been paralleled over the last several years by efforts to understand the actions of norepinephrine on neuronal function in the region. In this review, we will summarize the current state of these research areas. (C) 2013 Elsevier Ltd. All rights reserved.

【 授权许可】

Free