Auditory perception in the aging brain: the role of inhibition and facilitation in early processing

NEUROBIOLOGY OF AGING

卷:47

Article

Stothart, George¹  Kazanina, Nina¹ 

[1] Univ Bristol, Sch Expt Psychol, 12a Priory Rd, Bristol BS8 1TU, Avon, England

关键词: Aging;    Auditory event-related potentials;    Inhibition;    Speech;    Audio-visual;    N2;    P3a;   

DOI  :  10.1016/j.neurobiolaging.2016.06.022

来源: Elsevier

【 摘 要 】

Aging affects the interplay between peripheral and cortical auditory processing. Previous studies have demonstrated that older adults are less able to regulate afferent sensory information and are more sensitive to distracting information. Using auditory event-related potentials we investigated the role of cortical inhibition on auditory and audiovisual processing in younger and older adults. Across puretone, auditory and audiovisual speech paradigms older adults showed a consistent pattern of inhibitory deficits, manifested as increased P50 and/or N1 amplitudes and an absent or significantly reduced N2. Older adults were still able to use congruent visual articulatory information to aid auditory processing but appeared to require greater neural effort to resolve conflicts generated by incongruent visual information. In combination, the results provide support for the Inhibitory Deficit Hypothesis of aging. They extend previous findings into the audiovisual domain and highlight older adults' ability to benefit from congruent visual information during speech processing. (C) 2016 The Authors. Published by Elsevier Inc.

【 授权许可】

Free