Impact of infertility characteristics and treatment modalities on singleton pregnancies after assisted reproduction

REPRODUCTIVE BIOMEDICINE ONLINE

卷:13

Article

Poikkeus, Piia

关键词: assisted reproduction treatment;    elective single embryo transfer;    infertility characteristics;    IVF;    obstetric and neonatal outcome;   

DOI  :  10.1016/S1472-6483(10)62027-5

来源: Elsevier

【 摘 要 】

Obstetric and neonatal outcomes of assisted reproduction and control singletons were evaluated after taking into account treatment characteristics and infertility background. The elective single embryo transfer (eSET) group (n = 45) was compared with the compulsory single embryo transfer (cSET; n = 52), double embryo transfer (DET; n = 227) and control (n = 304) groups. Infertility-related prognostic factors for neonatal outcomes were also analysed. Data were collected with structured questionnaires at gestational week 20 and 8 weeks after delivery. Spontaneous onset of delivery was more typical of the eSET group than of cSET and DET groups (68.9 versus 52.0%, P = 0.02). Mean (+/- SD) gestation at birth (39.3 +/- 1.6 weeks) and mean birth weight (3470 +/- 505 g) of eSET singletons were comparable with other assisted reproduction groups, but gestational duration was lower than in the eSET group than in the control group (39.9 +/- 1.4; P < 0.05). However, numbers of preterm births and low birth weight infants were similar between groups. History of induced abortion increased risk of preterm birth (OR 4.5 and 95% CI 1.2-17.1) in assisted reproduction singletons. A small though clinically unimportant difference in gestational age at birth and birth weight between assisted reproduction and control singletons was found regardless of the number of embryos transferred.

【 授权许可】

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