Characterizing the practice of oocyte donation: a web-based international survey

REPRODUCTIVE BIOMEDICINE ONLINE

卷:28

Article

Weissman, Ariel¹  Leong, Milton²  Sauer, Mark V.³  Shoham, Zeev^4,5 

[1] Tel Aviv Univ, Sackler Fac Med, Edith Wolfson Med Ctr, Dept Obstet & Gynecol,IVF Unit, IL-69978 Tel Aviv, Israel

[2] Hong Kong Sanat & Hosp, Happy Valley, IVF Ctr, Hong Kong, Hong Kong, Peoples R China

[3] Columbia Univ, Coll Phys & Surg, Dept Obstet & Gynecol, New York, NY USA

[4] Kaplan Med Ctr, Reprod Med Unit, Rehovot, Israel

[5] Hebrew Univ Jerusalem, Hadassah Med Sch, IL-91010 Jerusalem, Israel

关键词: endometrial preparation;    endometrium;    oestrogen;    oocyte donation;    progesterone;   

DOI  :  10.1016/j.rbmo.2013.12.004

来源: Elsevier

【 摘 要 】

Although oocyte donation is widely practised, few interventions in this field are evidence based. The objective of this study was to describe the current practices for evaluation and treatment of oocyte donors and recipients worldwide. Through an IVF-focused website, an internet-based survey was addressed to physicians in IVF units worldwide. A total of 161 units responded, reflecting 14,890 annual oocyte donation cycles. The majority (83.3%) of centres perform genetic testing for oocyte donors, and in 94.6% of cycles, donors are <35 years old. Anonymous donors are most commonly used (91.3%) and 95.8% are fresh donations. In 51.4% of donor cycles, the gonadotrophin-releasing hormone (GnRH) antagonist protocol is used, and in 29.8% of these cycles, a GnRH agonist is prescribed for the ovulatory trigger. Recipient pituitary suppression is used in 76.7% of cycles, and oral oestrogen (86.4%) and vaginal progesterone (73.8%) are the preferred routes of administration for endometrial preparation. In the majority (51.5%) of cycles, a minimum endometrial thickness of >= 7 mm is required. This study reflects a relative lack of homogeneity in management of oocyte donors and recipients and highlights the need for developing a consensus in the practice of oocyte donation based upon evidence-based medicine. (C) 2014, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

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