Successful IVF programme after conservatively treated endometrial cancer

REPRODUCTIVE BIOMEDICINE ONLINE

卷:18

Article

Sodano, M.^1,2  Bogliatto, F.²  Morero, S.¹  Mosso, L.³  Torchio, B.³ 

[1] Reprod Med Ctr, CMR, Turin, Italy

[2] Chivasso City Hosp, Dept Obstet & Gynaecol, Turin, Italy

[3] Mauriziano Hosp, Dept Pathol Anat, Turin, Italy

关键词: cancer;    endometrium;    IVF;    pregnancy;   

DOI  :  10.1016/S1472-6483(10)60137-X

来源: Elsevier

【 摘 要 】

Some cases of successful pregnancy after conservative endometrial cancer management have been reported. This paper presents such a case. an infertile patient with conservatively treated endometrial cancer (stage 1 a grade 1) who conceived and carried a successful pregnancy after IVF treatment. The conservative treatment consisted of hysteroscopic biopsies and oral megestrol acetate 600 mg daily for 3 months. At the end of the treatment the endometrial cancer remitted to simple endometrial hyperplasia. IVF was performed immediately and 32 days after embryo transfer all intrauterine single gestational sac with fetal pole and heartbeat was detected by transvaginal ultrasound. The woman received routine obstetric care and a caesarean section was performed at 38 weeks of gestation. The histological evaluation after delivery showed no evidence Of recurrent disease. Twenty-six months after the delivery, the woman is healthy and free of the disease. It is concluded that conservative treatment of stage I a and grade 1 endometrial adenocarcinoma is;in available option in young women who wish to preserve their fertility.

【 授权许可】

Free