Assisted reproduction techniques in Latin America: the Latin American Registry, 2014

REPRODUCTIVE BIOMEDICINE ONLINE

卷:35

Article

Zegers-Hochschild, Fernando^1,2,3  Enrique Schwarze, Juan^3,4  Crosby, Javier^1,3  Musri, Carolina^1,3  Teresa Urbina, Maria^3,5 

[1] Clin Las Condes, Unit Reprod Med, La Fontecilla 441, Santiago, Chile

[2] Univ Diego Portales, Program Eth & Publ Policies Human Reprod, Eercito 260, Santiago, Chile

[3] Latin Amer Network Assisted Reprod REDLARA, Plaza Independencia 811, Montevideo, Uruguay

[4] Clin Monteblanco, Unit Reprod Med, Camino Farellones, Santiago 18780, Chile

[5] Unifertes, Av San Juan Bosco, Caracas, Venezuela

关键词: Assisted reproductive technology;    Epidemiology;    IVF-ICSI;    Latin America;    Perinatal outcome;    Registry;   

DOI  :  10.1016/j.rbmo.2017.05.021

来源: Elsevier

【 摘 要 】

Multinational data on assisted reproduction techniques [IVF and intractytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, pre-implantation genetic diagnosis and fertility preservation) were collected from 159 institutions in 15 Latin American countries. A total of 41.34% of IVF-CSI cycles were conducted in women aged 35-39 years and 23.35% in women aged 40 years and older. After removing freeze-all cases, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20.78% twins and 0.92% triplets and over. In oocyte donation, twins reached 28.93% and triplets 1.07%. Preterm deliveries reached 16.4% in singletons, 55.02% in twins and 76% in triplets. Perinatal mortality in 18,162 births was 23 per 1000 in singletons, 35 per 1000 in twins, and 36 per 1000 in high-order multiples. Elective single embryo transfer represented 2.63% of fresh transfers, with a 32.15% delivery rate per transfer. Elective double embryo transfer represented 23.74% of transfers, with a 41.03% delivery rate per transfer; 11,373 babies [62.6%] were singletons; 6398 [5.2%] twins, and 391 [.2%], triplets and more. Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred is mandatory. (C) 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

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