In-vitro maturation of germinal-vesicle oocytes and cryopreservation in metaphase I/II: a possible additional option to preserve fertility during ovarian tissue cryopreservation

REPRODUCTIVE BIOMEDICINE ONLINE

卷:8

Article

Isachenko, E ; Rahimi, G ; Isachenko, V ; Nawroth, F

关键词: cryopreservation;    germinal vesicle oocytes;    human ovarian tissue;    in-vitro maturation;   

DOI  :  10.1016/S1472-6483(10)61102-9

来源: Elsevier

【 摘 要 】

This study describes the possibility of combining two options in order to preserve female fertility: cryopreservation of human ovarian tissue and in-vitro matured germinal vesicle (GV) oocytes retrieved during tissue dissection. In contrast to ovarian tissue cryopreservation, the cryostorage of in-vitro matured unfertilized metaphaseI/II oocytes could be a more realistic option. This concept of preserving fertility before chemotherapy and/or radiotherapy without a long time delay could be an additional reason for favouring ovarian tissue cryopreservation. This concept is discussed in regard to two cases.

【 授权许可】

Free