Semen cryopreservation and usage rate for assisted reproductive technology in 898 men with cancer

REPRODUCTIVE BIOMEDICINE ONLINE

卷:32

Article

Muller, Iris¹  Ophuis, Ralph J. A. Oude²  Broekmans, Frank J. M.²  Lock, Tycho M. T. W.^1,3 

[1] Univ Med Ctr Utrecht, Dept Urol, Utrecht, Netherlands

[2] Univ Med Ctr Utrecht, Dept Reprod Med & Gynaecol, Utrecht, Netherlands

[3] Cent Mil Hosp, Dept Urol, Utrecht, Netherlands

关键词: assisted reproductive technology;    cancer;    cryopreservation;    semen;    usage rate;   

DOI  :  10.1016/j.rbmo.2015.11.005

来源: Elsevier

【 摘 要 】

An undesired side effect of cancer treatment is potential subfertility or infertility. Timely cryopreservation of semen is the best modality to ensure fertility. This retrospective data analysis established the usage rate of cryopreserved semen from cancer patients. Pubertal and post-pubertal patients who could become infertile as a result of cancer (treatment) were offered the option to cryopreserve semen prior to treatment. Of the 898 patients who cryopreserved their semen in our hospital, 96 (10.7%) used this for assisted reproductive technology. The live birth rates for intrauterine insemination, in-vitro fertilization, intracytoplasmic sperm injection and cryopreserved embryo transfer were 13%, 29%, 32% and 17%, respectively. Of all couples involved, 77% achieved parenthood, i.e. 60 of the 78 patients (with complete follow-up) fathered at least one child. (C) 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

Free