Impact of concurrent naturalistic pharmacotherapy on psychotherapy of complicated grief

PSYCHIATRY RESEARCH

卷:159

Article

Simon, Naomi M.¹  Shear, M. Katherine²  Fagiolini, Andrea³  Frank, Ellen³  Zalta, Alyson¹  Thompson, Elizabeth H.¹  Reynolds, Charles F., III³  Silowash, Russell³ 

[1] Massachusetts Gen Hosp, Ctr Anxiety & Traumat Stress Disorders, Boston, MA 02114 USA

[2] Columbia Univ, Sch Social Work, New York, NY USA

[3] Univ Pittsburgh, Sch Med, Western Psychiat Inst & Clin, Pittsburgh, PA USA

关键词: treatment;    antidepressant;    benzodiazepine;    complicated grief;    traumatic grief;    prolonged grief;   

DOI  :  10.1016/j.psychres.2007.05.011

来源: Elsevier

【 摘 要 】

Complicated grief (CG) is a debilitating syndrome that can be reliably identified, but there is a paucity of research examining treatment of CG. A targeted psychotherapy for complicated grief (CGT) was recently shown to be efficacious [Shear, K., Frank, E., Houck, P.R., Reynolds, C.F., 3rd, 2005. Treatment of complicated grief: a randomized controlled trial. Journal of the American Medical Association 293, 2601-2608]. We provide a detailed examination of the association of naturalistic pharmacotherapy use with treatment response and study completion in the psychotherapy study. Patients on an antidepressant medication were more likely to complete a full course of CGT (91% vs. 58% completed), while antidepressant use had no effect on completion rates for the comparator, interpersonal psychotherapy (70% vs. 77%). Our naturalistic data underscore the need for prospective, randomized controlled studies of CG pharmacotherapy and psychotherapy alone and in combination. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free