Brief interventions for improving adherence in schizophrenia: A pilot study using electronic medication event monitoring

PSYCHIATRY RESEARCH

卷:285

Article

Tessier, Arnaud^1,2  Dupuy, Maud^2,3  Bayle, Franck Jean⁴  Herse, Corinne¹  Lange, Anne-Catherine⁵  Vrijens, Bernard^5,6  Schweitzer, Pierre^2,7  Swendsen, Joel^2,7  Misdrahi, David^1,2 

[1] Ctr Hosp Charles Perrens, Pole Psychiat 347,121 Rue Bechade, F-33076 Bordeaux, France

[2] Univ Bordeaux, CNRS, Inst Neurosci Cognit & Integrat Aquitaine INCIA, UMR 5287, 146 rue Leo Saignat, F-33076 Bordeaux, France

[3] Univ Bordeaux, EA 4136 Handicap & Syst Nerveux, 146 Rue Leo Saignat, F-33076 Bordeaux, France

[4] Univ Paris V Descartes, Hop Sainte Anne, 1 Rue Cabanis, F-75014 Paris, France

[5] Univ Liege, Dept Publ Hlth, Pl 20 Aout 7, B-4000 Liege, Belgium

[6] AARDEX Grp, 24 Rue Cyclistes Frontiere, B-4600 Vise, Belgium

[7] PSL Res Univ, EPHE, 4-14 Rue Ferrus, F-75014 Paris, France

关键词: Schizophrenia;    Medication adherence;    Non-adherence;    Intervention;    Electronic monitoring;    Medication event monitoring system;   

DOI  :  10.1016/j.psychres.2020.112780

来源: Elsevier

【 摘 要 】

Poor medication adherence remains frequent in schizophrenia. The present study examined the efficacy of two month-long pilot interventions using the Medication Event Monitoring System (MEMS (R)). Thirty-three outpatients at high risk for relapse were randomized to receive a smartphone-based intervention, a nurse-based intervention, or treatment as usual. All patients then used the MEMS (R) to objectively measure medication adherence over six months. No differences were observed in adherence measures or relapse rates across the three groups. When using electronic medication monitoring as an objective measure of adherence, easily-implemented interventions may not significantly improve adherence in patients at high risk for relapse.

【 授权许可】

Free