Sitting time, physical fitness impairments and metabolic abnormalities in people with bipolar disorder: An exploratory study

PSYCHIATRY RESEARCH

卷:242

Article

Vancampfort, Davy^1,2  Sienaert, Pascal²  Wyckaert, Sabine²  De Hert, Marc²  Stubbs, Brendon^3,4  Probst, Michel¹ 

[1] Univ Leuven, KU Leuven, Dept Rehabil Sci, Leuven, Belgium

[2] Univ Leuven, KU Leuven, Univ Psychiat Ctr, Kortenberg, Leuven, Belgium

[3] South London & Maudsley NHS Fdn Trust, Physiotherapy Dept, London, England

[4] Kings Coll London, Inst Psychiat Psychol & Neurosci, Hlth Serv & Populat Res Dept, De Crespigny Pk, London, England

关键词: Bipolar disorder;    Depression;    Sitting;    Exercise;    Metabolic syndrome;    Physical fitness;   

DOI  :  10.1016/j.psychres.2016.05.023

来源: Elsevier

【 摘 要 】

A sedentary lifestyle is an independent risk factor for cardiovascular disease and mortality. Little is known however about sedentary behavior in people with bipolar disorder (BD). The primary aim of this study was to explore associations between sitting time (as a proxy for a sedentary lifestyle) and physical fitness and metabolic parameters in BD. A secondary aim was to investigate associations between psychiatric symptoms, psychotropic medication use and sitting time. Thirty-nine (219) participants (43.7 +/- 12.4 years) completed a full metabolic screening, the sitting time item of the International Physical Activity Questionnaire, the Quick Inventory of Depressive Symptomatology self-report and the Hypomania Checklist-32. Additionally participants performed the Eurofit-test battery and 6-min walk test. The mean time spent sitting per day for the entire sample was 7.0 +/- 3.0 h. A higher body mass index, worse physical fitness and higher antipsychotic medication dose were identified as independent predictors of higher levels of sitting behavior. The model explained 76.5% of the variability in the sitting time. Given that a sedentary lifestyle is an independent predictor of cardiovascular disease, future interventions specifically targeting time spend sitting are warranted in BD, with a particular emphasis on those with high body mass index and low fitness levels. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free